To study the health effects of coffee, King Gustav III of Sweden commuted the death sentences of a pair of twins on the condition that one drank 3 pots of coffee and the other tea for the rest of their lives.

About 1 million Japanese men are estimated to be locking themselves in their bedrooms for years, creating social and health problems, a condition called “Hikikomori.”

3.5% of cancer deaths worldwide are attributable to the consumption of alcohol. The World Health Organization has classified alcohol as a Group 1 carcinogen.